Genome instability can cause numerous diseases. Cells have effective DNA repair mechanisms at their disposal. A research team has now gained new insights into the DNA damage response.
Inside every cell, inside every nucleus, your continued existence depends on an incredibly complicated dance. Proteins are constantly wrapping and unwrapping DNA, and even minor missteps can lead to ...
NEAT1 itself does not repair DNA damage. However, as the Wurzburg team discovered, it enables the controlled release and activation of an RNA-binding DNA repair factor. In this way, the cell can ...
This important work shows how a simple geophysical setting of gas flow over a narrow channel of water can create a physical environment that leads to the isothermal replication of nucleic acids. The ...
One of the newest entrants into the market, Aptadir recently announced its plans to develop RNA therapies for rare cancers and genetic disorders ... Additional experiments revealed that they ...
This manuscript provides important new insight into the mechanisms underlying seasonal physiology, using medaka fish as a functional genetic model that naturally exhibits photoperiodic responses. The ...